Câu 41: NAPLEX: North American Pharmacist Licensure Examination

Alteplase is ordered for a 72 YOM who weighs 68kg for Ischemic stroke. The ER physician would like you to dose. As an ER pharmacist you know the dose is 0.9 mg/kg IV (not to exceed 90 mg); give 10% of the total dose as an IV bolus over 1 minute, then give the remaining 90% as an IV infusion over 60 minutes. After reconstitution, the concentration of Altaplace is 1mg/ml. How many ml is needed for the bolus and how many ml is needed for the infusion? Round to the nearest ml.

1. A. 6ml IV bolus, followed by 55mL IV over 60 minutes — đáp án hiện tại
2. B. 4ml IV bolus, followed by 57mL IV over 60 minutes
3. C. 3ml IV bolus, followed by 58mL IV over 60 minutes
4. D. 8ml IV bolus, followed by 52mL IV over 60 minutes
5. E. 9ml IV bolus, followed by 82mL IV over 60 minutes